Researchers create ‘mini-brains’ to model Lewy body dementia and identify treatments
The drug working 3D computational model illustrating the binding interactions between α-SYN aggregates and candidate drugs (D1, D3, D4, and ...
Tag: treatments
Computer simulation mimics how the brain develops neurons, paving the way for future disease treatments
3D mechanistic ABM for neuronal growth. Panel a shows the agent-based discretization and early stage of a neuron (pyramid cell) ...
Newly discovered genetic marker could pave the way for future treatments for Alzheimer’s disease
While previous studies have made progress in identifying genetic variants associated with amyloid deposits, understanding the genetic drivers of tau ...
Scientists discover new series of SARS-CoV-2 Mpro inhibitors for potential new treatments against COVID-19
Design of cysteine protease inhibitors. (A) Tripeptide-based interleukin-1β converting enzyme inhibitor. (B) Main compound of Pfizer coronavirus protease reported in ...
New technique that makes competition between tumor cells visible may help personalize multiple myeloma treatments
A clonal competition assay showing populations of cells with different mutations. Depending on the mutation, each population of cells is ...
Failed CAR T cell trial could unlock multiple treatments for acute myeloid leukemia
Exposure of AML to cytokines results in depletion of CART-123. Credit: Natural medicine (2024). DOI: 10.1038/s41591-024-03271-5 In the clinical battle ...
Artificial proteasome offers prospects for new treatments against trichomoniasis
Recombinant proteasome of the parasite Trichomonas vaginalis, successfully produced in insect cells. The structure of the complex, composed of 28 ...
Analysis calculates $725 million economic potential from expanded access to cancer treatments
Relationship between the cost of treatment and GDP per capita. Credit: The Lancet Oncology Commission A recent analysis, published in ...
Treatments that maintain healthy synapses may help prevent and alleviate symptoms of prion disease
Differentiation of human iPSCs into cortical pyramidal neurons via dual SMAD inhibition. Credit: Stem Cell Reports (2024). DOI: 10.1016/j.stemcr.2024.08.010 Genetic ...
Why do some Parkinson’s treatments affect decision making?
Mice with Parkinson's disease treated with pramipexole show poor decision-making abilities in a gambling task, as seen on the left. ...
