Researchers develop new method to deliver RNA and drugs into cells
Ionizable analogues of fulvestrant were formulated into nanoparticles with cholesterol, DSPC and DMG-PEG (molar ratio 50:38.5:10:1.5) to encapsulate siRNA (FXNP). ...
Tag: RNA
New type of RNA could improve vaccines and cancer treatments
Development and characterization of a fully modified sRNA vaccine against SARS-CoV-2. Credit: Biotechnology of nature (2024). DOI: 10.1038/s41587-024-02306-z It all ...
RNA editing plays a critical role in fruit flies’ sense of smell and social interactions
Recoding the Island27 Val is conserved across Drosophila species. Credit: Scientific progress (2024). DOI: 10.1126/sciadv.adi9101 Think of your DNA as ...
Study finds RNA molecule controls butterfly wing coloration
Shown here is a long-winged butterfly whose wing (right) has been modified using CRISPR gene editing, resulting in a radical ...
Scientists unlock secrets of how a key protein converts DNA into RNA
The researchers took pictures of their RNA polymerase crystals using a special type of microscope that uses UV light. This ...
RNA loop closure holds promise for more stable and effective RNA-based therapies
Engineering of RNAc and RNAi. Credit: Nature Biomedical Engineering (2024). DOI: 10.1038/s41551-024-01245-z New methods for shaping RNA molecules into circles ...
Study reveals role of RNA in regulating gene expression in cancer cells
Credit: Molecular cell (2024). DOI: 10.1016/j.molcel.2024.07.032 Scientists have discovered how interactions between RNA and the essential enzyme TOP1, which is ...
New RNA editing tool could improve cancer treatment
Credit: Cell (2024). DOI: 10.1016/j.cell.2024.01.035 Cancer cell therapies can be potentially improved with a CRISPR RNA-editing platform, according to a ...
Special RNA has been shown to suppress the formation of breast cancer cells
Credit: Cell Reports (2024). DOI: 10.1016/j.celrep.2023.113644 Breast cancer is the most common cancer in women. The development of breast cancer ...
Disruption of RNA editing mimics early-stage disease without virus involvement
Image of a mouse pancreas with disrupted RNA editing in beta cells, showing massive inflammation destroying an islet of Langerhans. ...
