New AI model designs proteins to deliver gene therapy
ProteinVAE architecture. Encoder: The pre-trained language model (e.g., ProtBert) converts the input one-hot encoded sequences to amino acid-level representation H. ...
Tag: proteins
Discovery of the highly specific attachment of fatty acids to proteins
Fluorescence imaging of C. elegans fed with a new chemical probe developed in this study: a branched-chain fatty acid analogue. ...
Study discovers how a system of proteins helps Salmonella survive inside macrophages
Scanning electron micrograph of Salmonella typhimurium invading a human epithelial cell. Credit: Journal of Bacteriology (2023). DOI: 10.1128/jb.00183-23 Salmonella is ...
Targeting the mRNA of “undruggable” proteins in the fight against Parkinson’s disease
Credit: Pixabay/CC0 Public domain Researchers at the Scripps Research Institute in Florida have developed a new method to counteract levels ...
New mapping method illuminates drug sites on proteins
A protein with unknown binding sites (left), versus a protein with high-resolution binding site mapping (right). Credit: Scripps Research Identifying ...
Structures of proteins linked to Parkinson’s disease provide a framework for understanding how they work together
Credit: Unsplash/CC0 Public domain Scientists at St. Jude Children's Research Hospital have revealed the complex structure of two proteins linked ...
Using molecular cookie cutters to visualize the organization of membrane proteins
With Native-nanoBleach, nanodiscs containing target membrane proteins and their native cell membrane environment are cut from the cell membrane. Attached ...
