New protein interactions could serve as a biomarker for heart disease
Structured illumination microscopy of atrial cardiomyocytes isolated from wild-type (A) and heterozygous Mybphl-null mice (B) reveals localization of MyBP-HL (red) ...
Tag: protein
Research team reports observing vibrational spectra of a single protein using infrared nanospectroscopy
Single-protein infrared vibrational spectroscopy (left) Schematic of near-field infrared spectroscopy measuring a single protein. (Right) The structure of the F1-ATPase ...
Variants of the synaptic scaffolding protein PPFIA3 discovered cause a new syndromic neurodevelopmental disorder
Credit: Pixabay/CC0 Public domain An international collaborative study recently discovered that variants in the PPFIA3 gene cause a previously unknown ...
Protein partners identified as potential keys to fetal bone development
Graphical summary. Credit: Development cell (2023). DOI: 10.1016/j.devcel.2023.11.029 A pair of proteins, YAP and TAZ, have been identified as drivers ...
Breakthrough in the design of complex all-α protein structures
Credit: Nature Structural and molecular biology (2024) A team of researchers has developed an innovative method to engineer fully α ...
The HKDC1 protein appears to be essential for the maintenance of two subcellular structures of mitochondria, mitochondria and lysosomes.
Overview: Mitochondrial and lysosomal stress stimulates nuclear translocation of TFEB, followed by increased expression of HKDC1. HKDC1 stabilizes PINK1 through ...
Study identifies ‘visual system’ protein for circadian rhythm stability
Tenm3 expression in the SCN is highest in VIP cells. (A) RNAscope in situ hybridization in coronal sections of P5 ...
Protein allows poison dart frogs to accumulate toxins safely, study finds
The poisonous frog Diablito, Oophaga sylvatica, is native to Colombia and Ecuador. Credit: Marie-Thérèse Fischer (CC BY 4.0) Scientists have ...
Secret Vulnerabilities of Cancer’s ‘Death Star’ Protein Revealed
A three-dimensional image showing the human protein KRAS (blue) interacting with RAF1 (yellow), one of its main partners. The blue ...
Researchers discover for the first time a link between a hemoglobin-like protein and normal heart development
cygb2 The mutant phenotype exhibits organ laterality defects. A CRISPR/Cas9-mediated genome editing cygb2. Two different gRNAs were targeted to exon ...
