Researchers Discover Neuroprotective Function of Tau Protein
Overexpression of hTau in glia disrupts LDs and glial cell morphology in response to neuronal ROS. Credit: Neuroscience of Nature ...
Tag: protein
New anti-cancer ‘degrader’ targets protein key to childhood leukemia
Discovery of a first-rate and very powerful ENL PROTAC degrader, recruiting VHL, MS41. Credit: Scientific progress (2024). DOI: 10.1126/sciadv.ado1432 Scientists ...
Scientists unlock secrets of how a key protein converts DNA into RNA
The researchers took pictures of their RNA polymerase crystals using a special type of microscope that uses UV light. This ...
Study shows electrically activated protein regulates spermatogenesis
Maturing sperm perceive “electrical signals.” Immature sperm perceive “electrical signals,” and the lipid composition of the cell membrane is appropriately ...
New research elucidates a master regulator of protein production
Molecular model of the cotranslational multi-enzyme complex comprising the ribosome (blue and gray), the NAC chaperone complex (yellow and orange), ...
Dual protein analysis approach offers potential way to slow cancer growth
Chemoproteomics (ABPP) methods identify a stereoprobe that interacts with a cysteine in the cell cycle protein MAD2L1BP and disrupts its ...
New device monitors levels of inflammation-associated C-reactive protein in real time
Graphic summary. Credit: ACS sensors (2024). DOI: 10.1021/acssensors.4c00249 Since inflammation is the body’s natural immune response to disease or infection, ...
How insulin, zinc and pH can block harmful protein clumps linked to type 2 diabetes
TEM images of IAPP and insulin aggregates. Credit: Biology of communications (2024). DOI: 10.1038/s42003-024-06388-y An estimated 462 million people worldwide ...
Cryo-ET study elucidates protein folding helpers in their natural environment
In situ structures of chaperonin complexes. Credit: Nature (2024). DOI: 10.1038/s41586-024-07843-w Cryo-electron tomography (cryo-ET) makes it possible to visualize and ...
Researchers teach artificial intelligence about protein folding frustration
Chemical structure of thiamine pyrophosphate and protein structure of transketolase. Thiamine pyrophosphate cofactor in yellow and substrate xylulose 5-phosphate in ...
