AI-driven approach challenges traditional views on protein structure
Presentation of the Urfold model and the DeepUrfold approach to identify domains likely to reflect the phenomenon of “architectural similarity ...
Tag: protein
Cellular agriculture research succeeds in growing pig adipose tissue on rye protein scaffolds
Schematic illustration of cultured porcine adipose tissue based on sponge-like secalin scaffolds created using the model leaching method. This process ...
Promising Alzheimer’s drug candidate prevents tau protein buildup in lab and fruit fly studies
The brain of a 7-day-old fruit fly with Tau expressed in a neural circuit used by the fly in olfactory ...
Filament structure activates and regulates CRISPR-Cas “protein scissors”
The cryogenic electron microscope structure of the A4p-activated CalpL protein filament (green) (purple) from Candidatus Cloacimonas acidaminovorans (PDB ID: 9EYJ). ...
Researchers determine how a protein contributes to human immune defense against RNA viruses
NMR and ITC analysis of RNA binding by the TRIM25 PRY/SPRY domain. Credit: Natural communications (2024). DOI: 10.1038/s41467-024-52918-x An international ...
Protein study reveals how tiny shrew achieves resting heart rate of 1,020 beats per minute
The little American shrew, which has an incredibly high resting heart rate. Credit: Joe Pontecorvo The shrew's resting heart rate ...
AI ‘liquid biopsies’ using cell-free DNA and protein biomarkers could aid early detection of ovarian cancer
Credit: Carolyn Hruban, Ph.D. A blood test using artificial intelligence (AI) to detect cancer-related genetic changes and protein biomarkers could ...
How a protein keeps gene clusters silent in the cell nucleolus
Credit: Scientific advances (2024). DOI: 10.1126/sciadv.ado1662 In a discovery that sheds light on the complex mechanisms of gene regulation, EPFL ...
Shedding light on a decades-old protein sorting mystery
Structure of an epithelial cell, with its apical face at the top and its basolateral faces at the bottom and ...
Paving the way for new treatments with a tool that builds 3D structures of protein complexes
A look at Cryo2Struct’s automated prediction workflow. Credit: Nature Communications (2024). DOI: 10.1038/s41467-024-49647-6 A University of Missouri researcher has created ...
