Peptide-guided nanoparticles deliver mRNA to neurons
Abstract. Credit: Nano letters (2024). DOI:10.1021/acs.nanolett.4c05186 Penn engineers have modified lipid nanoparticles (LNPs) – the revolutionary technology behind mRNA COVID-19 ...
Tag: mRNA
mRNA vaccines against epidemics can be synthesized in less time using a new technique
The phosphorylation reagent with a hydrophobic nitrobenzyl tag allows the production of high purity fully chemically synthesized mRNAs and transcriptionally ...
Blood test study may help improve performance and reduce side effects of mRNA vaccines
The researchers processed blood samples to obtain plasma and studied the mRNA components in the plasma. Credit: Dr Yi (David) ...
Scientists develop mRNA vaccine that protects mice against gut bacteria C. difficile
Model figure. (A) C. difficile toxins target the intestinal epithelium and cause severe pathology and gastrointestinal disease leading to morbidity ...
New mRNA and gene editing tools offer hope for dengue virus treatment
Schematic of the composition and mechanism of action of an anti-DENV drug LbuCas13a expressed by mRNA. Credit: Microbiology of nature ...
Stabilizing mRNA vaccines for delivery to cells
Credit: Advanced Materials Science and Technology (2023). DOI: 10.1080/14686996.2023.2170164 Vaccines and therapies based on messenger RNA could be more easily ...
mRNA technology could be possible treatment for rare genetic liver disease
Credit: CC0 Public domain Harnessing technology used in COVID-19 vaccines, a team led by scientists from UCL, King's College London ...
Targeting the mRNA of “undruggable” proteins in the fight against Parkinson’s disease
Credit: Pixabay/CC0 Public domain Researchers at the Scripps Research Institute in Florida have developed a new method to counteract levels ...
Researchers discover new lipid nanoparticles that show muscle-specific mRNA delivery and reduce off-target effects.
A team of researchers based at the Leslie Dan Faculty of Pharmacy at the University of Toronto (U of T) ...
