Molecular ‘superglue’ holds promise for cancer drug discovery platform
Hit identification and optimization strategy. a Heatmap of selected screening results on a panel of acute leukemia (AL) and medulloblastoma ...
Tag: Molecular
One-step synthesis of the most common, but highly complex, antibiotic molecular scaffold
Palladium-catalyzed generation of Fischer carbene complexes and its use for the synthesis of β-lactams. Credit: Mamoru Tobisu Although we seem ...
New research provides molecular insight into mechanisms behind pigmentation variation
Sarah Tishkoff, of the University of Pennsylvania, led a team of researchers who uncovered key insights into the molecular basis ...
Researchers identify molecular link between gut bacteria and excitatory brain signaling in C. elegans
B12 produced by intestinal bacteria suppresses the hyperactive behavior of unc-2(gof) mutants. Credit: Natural cellular biology (2024). DOI: 10.1038/s41556-023-01299-2 A ...
Researchers reveal molecular mechanism of coronavirus-induced cytokine storm
SARS-CoV-2 stabilizes host mRNAs to induce a cytokine storm. Credit: Xue Yuanchao’s group Over the past four years, the pathogen ...
Researchers discover unexpected molecular pattern in fragile X syndrome
Credit: Cell (2023). DOI: 10.1016/j.cell.2023.11.019 Researchers have discovered new disrupted genes and an unexpected molecular pattern — called BREACHes — ...
Research reveals molecular origins of how a key drug target works
By examining each individual component of the β2 adrenergic receptor and seeing how they contribute to the overall function of ...
Using molecular cookie cutters to visualize the organization of membrane proteins
With Native-nanoBleach, nanodiscs containing target membrane proteins and their native cell membrane environment are cut from the cell membrane. Attached ...
Using next-generation CRISPR tool, scientists create unprecedented molecular map of human immune response
Carl Ward, PhD, a postdoctoral researcher in the Marson Lab at the Gladstone Institutes, was co-first author of the landmark ...
Molecular fossil study sheds light on changing dietary strategy in ancient life
Overview of the Neoproterozoic sterane record. The geological time scale is shown on the left, with dates in hundreds of ...
