Global clinical trial shows improved survival rates for common childhood leukemia
Bone marrow aspirate showing acute myeloid leukemia. Several explosions have Auer stems. Credit: Wikipedia Just days before his fourth birthday, ...
Tag: leukemia
Study identifies genetic factors crucial in acute myeloid leukemia survival in black patients
Previously unreported mutations in the PHIP gene and representation of the fusion gene landscape. Credit: Natural genetics (2024). DOI: 10.1038/s41588-024-01929-x ...
Failed CAR T cell trial could unlock multiple treatments for acute myeloid leukemia
Exposure of AML to cytokines results in depletion of CART-123. Credit: Natural medicine (2024). DOI: 10.1038/s41591-024-03271-5 In the clinical battle ...
Promising cell therapy offers hope for relapsed or refractory T-cell leukemia
Antileukemic activity of anti-CD7 PEBL-CAR T cells. Credit: Natural medicine (2024). DOI: 10.1038/s41591-024-03228-8 A new cell therapy, targeting CD7 in ...
Discovery of key gene offers new hope for treatment of chronic myelogenous leukemia
Schematic image, showing R-loop resolution by REXO5 (left) and inhibition of R-loop resolution by REXO5 mutation (right). Credit: Leukemia (2024). ...
Radon, even at levels below EPA mitigation guidelines, is linked to childhood leukemia
Graphical summary. Credit: Total Environmental Science (2024). DOI: 10.1016/j.scitotenv.2024.176288 A study of more than 700 counties in several U.S. states ...
New anti-cancer ‘degrader’ targets protein key to childhood leukemia
Discovery of a first-rate and very powerful ENL PROTAC degrader, recruiting VHL, MS41. Credit: Scientific progress (2024). DOI: 10.1126/sciadv.ado1432 Scientists ...
New research poised to transform approach to diagnosis and treatment of acute leukemia in children
Genomic classification of ETP/ETP-like ALL. Credit: Nature (2024). DOI: 10.1038/s41586-024-07807-0 Researchers from Children's Hospital of Philadelphia (CHOP), St. Jude Children's ...
Novel bispecific design improves CAR T cell immunotherapy for childhood leukemia
Graphical summary. Credit: Cell Reports Medicine (2024). DOI: 10.1016/j.xcrm.2024.101422 Scientists at St. Jude Children's Research Hospital have improved chimeric antigen ...
Targeting treatment resistance in chronic lymphocytic leukemia with a compound that goes beyond current BTK inhibitors
Credit: Unsplash/CC0 Public domain New research from the Sylvester Comprehensive Cancer Center at the University of Miami Miller School of ...
