Key genes linked to DNA damage and human diseases discovered
Loss of Dscc1 leads to early developmental defects and increased genomic instability. AHeart and liver abnormalities Dscc1−/− E14.5 mouse embryos. ...
Tag: genes
Gene’s role in achieving and maintaining muscle mass revealed in new study
Model for BCL6-mediated control of skeletal muscle proteostasis. BCL6-mediated transcriptional regulation controls the expression of atrogenic regulators to establish and ...
Immune genes are altered in the blood of Alzheimer’s patients
Credit: Neuron (2024). DOI: 10.1016/j.neuron.2024.01.013 A new study from Northwestern Medicine has found that the immune system in the blood ...
New tool improves search for disease-causing genes
DNA, which has a double helix structure, can have many mutations and genetic variations. Credit: NIH A new statistical tool ...
Harnessing skin cancer genes to heal hearts
Two cross sections of engineered rat heart tissue showing the BRAF mutation at work. The BRAF-altered cell on the right ...
Newly identified genes for depression could lead to new treatments
Schematic diagram of the analyzes in this study. We included data from 21 cohorts of diverse ancestry. We divided individuals ...
Research finds one of the deleted genes linked to Williams syndrome is responsible for mitochondrial function in the brain
ROS and apoptosis-related markers are altered throughout the cortex of cKO mice compared to controls. The mRNA levels of ROS-related ...
Novel roles for autophagy genes in cellular waste management and aging
Credit: Natural aging (2024). DOI: 10.1038/s43587-023-00548-1 Autophagy, which declines with age, may hold more mysteries than researchers previously suspected. In ...
Team discovers relationship between timing of DNA replication and how genes fold into 3D structures inside the cell nucleus
RT appears gradually during preimplantation development of the mouse. AOverview of single-cell Repli-seq used to generate RT profiles from single ...
Changing the behavior of living mice by modifying brain genes
Restoration of spine density and impairment of synaptic transmission in medial layers II and III neurons of the PFC in ...
