Discovery of key gene offers new hope for treatment of chronic myelogenous leukemia
Schematic image, showing R-loop resolution by REXO5 (left) and inhibition of R-loop resolution by REXO5 mutation (right). Credit: Leukemia (2024). ...
Tag: gene
Comprehensive gene activity mapping brings hope to chronic pain patients
Temporal molecular dynamics of nociceptors and pain states during neuropathic pain. Credit: Natural communications (2024). DOI: 10.1038/s41467-024-52052-8 Researchers at Karolinska ...
Study reveals key role of TRIO gene in epileptic encephalopathy
Defective migration of MGE-derived cortical INs into Trio–/– embryos. Credit: Molecular Psychiatry (2024). DOI: 10.1038/s41380-024-02742-y What are the molecular and ...
Scientists decode a key mutation in many cancers, highlighting the increased role of RNA in human gene expression
Credit: Unsplash/CC0 Public domain Inside every cell, inside every nucleus, your existence depends on an incredibly complicated dance. Proteins are ...
The structure of a eukaryotic CRISPR-Cas homolog, Fanzor2, shows promise for gene editing
Elizabeth Kellogg, PhD, Department of Structural Biology at St. Jude, used cryo-EM to study the evolutionary journey of Fanzor2, a ...
How a protein keeps gene clusters silent in the cell nucleolus
Credit: Scientific advances (2024). DOI: 10.1126/sciadv.ado1662 In a discovery that sheds light on the complex mechanisms of gene regulation, EPFL ...
Single-dose gene therapy could change lives of adults with hemophilia B
Credit: Pixabay/CC0 Public Domain Adults with hemophilia B saw their number of bleeding episodes reduced by an average of 71% ...
Eyesight improves 100-fold after gene therapy trial
Credit: Unsplash/CC0 Public Domain The vision of people with a rare inherited disease that causes vision loss in childhood improved ...
New mRNA and gene editing tools offer hope for dengue virus treatment
Schematic of the composition and mechanism of action of an anti-DENV drug LbuCas13a expressed by mRNA. Credit: Microbiology of nature ...
Gene regulation study finds coordination between basic cellular processes is lost with age
Representative gene-gene relationships change with age, captured by pairwise correlation and a GRN-based approach. Credit: Aging of nature (2024). DOI: ...
