Researchers develop new method to deliver RNA and drugs into cells
Ionizable analogues of fulvestrant were formulated into nanoparticles with cholesterol, DSPC and DMG-PEG (molar ratio 50:38.5:10:1.5) to encapsulate siRNA (FXNP). ...
Tag: drugs
Solving the problem of side effects of siRNA-based drugs for the treatment of genetic diseases
A formamide modification (yellow) to a siRNA therapeutic agent (blue) prevents it from binding to non-targeted mRNA, allowing treatment with ...
Detection algorithm predicts best drugs for genetic disorders and cancer
Ben Lehner (left) and Fran Supek (right), co-corresponding authors of the study. Credit: Centre for Genomic Regulation A computer model ...
Deadly toxin from sea snails could hold key to making better drugs
Ho Yan Yeung, Ph.D., first author of the study (left), and Thomas Koch, Ph.D., also an author of the study ...
Shortage of cancer drugs: passionate American coach loses his fight
A high school coach who fought to the end against an aggressive cancer to continue training his young players has ...
Use of HIV prevention drugs doubles with combination of digital health interventions, study finds
Credit: Pixabay/CC0 Public domain A UCLA Health study found that a combination of one-on-one telehealth coaching interventions, peer support forums ...
New model identifies drugs that should not be taken together
Credit: CC0 Public domain Any medication taken orally must pass through the lining of the digestive tract. Transport proteins on ...
Scientists code ChatGPT to design new drugs
Graphical summary. Credit: Drugs (2024). DOI: 10.3390/ph17020161 Generative AI platforms, from ChatGPT to Midjourney, have made headlines in 2023. But ...
Three thirty-year-olds found frozen to death: “several” illegal drugs found in their system
Three 30-year-olds from Missouri found frozen to death in their friend's backyard may have consumed a cocktail of illegal drugs ...
A “heart-on-a-chip” to test the cardiac toxicity of chemotherapies and other anticancer drugs
Cedars-Sinai researchers used a unique 3D chip to examine the effects of chemotherapy on different types of heart cells. Credit: ...
