Designing drugs targeting “twin” cancer proteins
A drug candidate (pink) was found to bind to the pocket between the cancer-related protein CCNE1 (green) and its partner ...
Tag: drugs
Two studies reveal that the SARS-CoV-2 virus becomes resistant to antiviral drugs used to treat patients
Susceptibility of SARS-CoV-2-nsp5T169Insp12V792I virus to nirmatrelvir and remdesivir in vitro. Credit: Natural communications (2024). DOI: 10.1038/s41467-024-51924-3 Two studies have found ...
AI model identifies existing drugs that can be repurposed to treat rare diseases
Credit: Pixabay/CC0 Public Domain There are over 7,000 rare and undiagnosed diseases worldwide. Although each condition affects only a small ...
What do anti-obesity drugs do to the body?
Wegovy, Mounjaro, Ozempic... These drugs are driving the pharmaceutical industry crazy and fueling the hopes of millions of patients suffering ...
Revolution or Mirage? Controversy Over New Drugs for Alzheimer’s Disease
Credit: Unsplash/CC0 Public Domain Two new drugs, the first capable of slowing the debilitating progression of Alzheimer's disease, are at ...
Changes in the chromosomes of cancer cells may increase their sensitivity to anticancer drugs
Characterization of paired aneuploid and pseudo-diploid clones. Credit: Nature Communications (2024). DOI: 10.1038/s41467-024-52176-x Two complementary studies conducted by Tel Aviv ...
Weight-loss drugs may help fight fatty liver disease
Graphic summary. Credit: Cellular metabolism (2024). DOI: 10.1016/j.cmet.2024.07.023 To combat fatty liver disease, researchers are looking for every solution they ...
Researchers develop new method to deliver RNA and drugs into cells
Ionizable analogues of fulvestrant were formulated into nanoparticles with cholesterol, DSPC and DMG-PEG (molar ratio 50:38.5:10:1.5) to encapsulate siRNA (FXNP). ...
Solving the problem of side effects of siRNA-based drugs for the treatment of genetic diseases
A formamide modification (yellow) to a siRNA therapeutic agent (blue) prevents it from binding to non-targeted mRNA, allowing treatment with ...
Detection algorithm predicts best drugs for genetic disorders and cancer
Ben Lehner (left) and Fran Supek (right), co-corresponding authors of the study. Credit: Centre for Genomic Regulation A computer model ...
