New research with implications for drug discovery allows visualization of the smallest protein clusters
The bright white dots represent tiny clusters of proteins detected by CluMPS. Credit: Thomas R. Mumford Penn engineers have developed ...
Tag: drug
‘Suspended Animation’ Drug Could Aid Organ Transplantation, Survival After Traumatic Injury
Uptake and activity of SNC80 at the delta opioid receptor. A. Distribution of SNC80 in Xenopus tadpoles after 1 and ...
New drug could protect brain from damage caused by repeated concussions
The p17 transporter in mice leads to the accumulation of damaged and disorganized membranes in axonal mitochondria. This accumulation ultimately ...
Research team discovers potential drug for Alzheimer’s disease
Molecular docking predicts a CLEAR DNA-binding region in ApoE4. a The DNA binding region of ApoE4, as defined by molecular ...
Influenza virus variants resistant to new antiviral drug candidate lose pathogenicity, study finds
Credit: Pixabay/CC0 Public domain Influenza A viruses with induced resistance to a new antiviral drug candidate were found to be ...
Building a DNA nanoparticle that is both a carrier and a drug
Illustration of the genetic construct used in this study and the process of generating scaffold and DNA nanoparticles via aPCR ...
New drug stops growth of aggressive breast cancer in preclinical study
CDDD11-8 inhibits the proliferation of patient-derived mammary organoid models. Credit: Oncogene (2023). DOI: 10.1038/s41388-023-02892-3 A promising drug could lead to ...
Oregon, pioneer of drug decriminalization in the United States, in full doubt
In the heart of Portland, Eli Arnold arrests a homeless man who is smoking meth. But instead of handcuffs, the ...
Proteins suggest a pathway to reduce drug resistance in a form of cancer
Credit: Cell Reports Medicine (2024). DOI: 10.1016/j.xcrm.2023.101359 Doctors have nearly a dozen new targeted drugs to treat patients with acute ...
Combination drug therapy shows promise for treatment-resistant cancer
Christine Pratilas, MD, in the lab. Credit: Frederick W. Dubs, Johns Hopkins Pathology Photography & Graphics A combination of two ...
