New class of ‘intramolecular bivalent glue’ could transform cancer drug discovery
IBG1 degrades BRD2 and BRD4 independently of DCAF15. AStructure of IBG1. b, BET protein degradation activity of IBG1. HEK293 cells ...
Tag: drug
Former Honduran president on trial in New York for alleged drug trafficking
The exceptional trial of former Honduran President Juan Orlando Hernandez for alleged drug trafficking to the United States, including smuggling ...
New insights into an old IBD drug could improve treatments
Graphical summary. Credit: Cell Reports Medicine (2024). DOI: 10.1016/j.xcrm.2024.101431 Although it is one of the oldest medications used to treat ...
Drug overdose deaths higher among U.S. visitors to Florida than rest of U.S., researchers say
Credit: Unsplash/CC0 Public domain U.S. visitors who died in Florida to the state were 63% more likely to have died ...
Clinical trial shows rheumatoid arthritis drug could prevent disease
Credit: Unsplash/CC0 Public domain A drug used to treat rheumatoid arthritis could also prevent the disease in people deemed at ...
Drug used for cocaine addiction could pave the way for new treatment for advanced colon cancer
Multi-omics characterization of the cancer-selective effect of VXN on cellular functions. Credit: Natural cancer (2024). DOI: 10.1038/s43018-024-00727-y A cutting-edge new ...
How a new drug pushes the HIV capsid to the breaking point
Lenacapavir causes the HIV capsid to rupture before it can carry its genetic material to the host cell's nucleus. Credit: ...
UTI drug gepotidacin performs well in clinical trials compared to nitrofurantoin
Credit: Pixabay/CC0 Public domain A team of medical researchers affiliated with British multinational pharmaceutical and biotechnology company GlaxoSmithKline (GSK) found ...
Cancer drug opens new avenue for treating Parkinson’s disease
Graphical summary. Credit: Cellular chemical biology (2024). DOI: 10.1016/j.chambiol.2024.01.007 Once entering the body, drugs, in addition to fulfilling their therapeutic ...
Drug reuse research offers new hope in fight against RSV
Identification of candidates for drug repurposing. A Selection and validation procedure. B HEp-2 cells were infected with rHRSV-A-GFP29 in the ...
