New platform provides in-depth insights into T cell responses against a new cancer vaccine
Development and comparative analysis of a TCR activation reporting system. (A) Schematic illustrating the construction of a TCR reporter cell ...
Tag: cancer
Italian scientists reveal resistance mechanism used by pancreatic cancer cells to escape therapies
Pancreatic cancer cells (blue) growing as a sphere wrapped in membranes (red). Credit: National Cancer Institute Italian scientists from the ...
Strategies to protect breast cancer patients from lymphedema
Credit: Unsplash/CC0 Public domain As part of a global effort to improve the lives of breast cancer survivors, new health ...
Innovative modeling can help breast cancer patients who don’t respond to treatment
The computer model predicts synergistic combinations of drugs. a–f Drug synergy model prediction was generated using the drug interaction coefficient ...
New drug stops growth of aggressive breast cancer in preclinical study
CDDD11-8 inhibits the proliferation of patient-derived mammary organoid models. Credit: Oncogene (2023). DOI: 10.1038/s41388-023-02892-3 A promising drug could lead to ...
Researchers identify protein linked to metastasis in pancreatic cancer
Micrograph showing a pancreatic tumor with experimentally depleted En1 levels, which reduces metastatic activity. Credit: Jihao Xu/UC Davis Pancreatic cancer ...
Proteins suggest a pathway to reduce drug resistance in a form of cancer
Credit: Cell Reports Medicine (2024). DOI: 10.1016/j.xcrm.2023.101359 Doctors have nearly a dozen new targeted drugs to treat patients with acute ...
New discovery could deliver a double punch against cancer
Graphical summary. Credit: Cell (2024). DOI: 10.1016/j.cell.2024.01.008 A multinational team of researchers led by Columbia University has discovered that tumors ...
Immune cells lose their ‘killer instinct’ in cancer tumors, but their functionality can be reawakened
Evidence of dysfunctional NK cells in human CRC was sought through bioinformatics analysis of publicly available datasets as well as ...
For diabetes and liver cancer, study suggests new screening guidelines
Collagen fibers in a three-dimensional hydrogel (left panel). When advanced glycation end products – a byproduct of poorly controlled diabetes ...
