Semaglutide, present in Ozempic and Wegovy, is effective in weight loss. In addition, it would reduce major cardiovascular events by 20% in overweight or obese patients without a history of diabetes.
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In addition to its possible anti-cancer properties, researchers attribute protective effects to Ozempic and Wegovy against cardiovascular risk. These two antidiabetic drugs also used for weight loss contain the same active ingredient, semaglutide.
“ We know that overweight and obesity increase the risk of cardiovascular events. However, while the reduction of cardiovascular diseases by the treatment ofhypercholesterolemiahypercholesterolemiaof the’high blood pressurehigh blood pressure and diabetesdiabetes is a common practice, the concept of treating obesity to reduce cardiovascular complications has been hampered “, explained Michael Lincoff, co-author of a new study published in the New England Journal of Medicine.
A possible route to treating the harmful effects of obesity and diabetes
The test Select included more than 17,000 participants over the age of 45 who had pre-existing cardiovascular disease and a BMI of at least 27, but who had no history of diabetes. The results show that a weekly dose of 2.4 mg of semaglutide allows a 20% reduction in major adverse cardiovascular events (cardiovascular death, myocardial infarctionmyocardial infarction And StrokeStroke non-fatal) in these overweight or obese patients not diabeticsdiabeticscompared to a placeboplacebo. Follow-up lasted 39.8 months in total.
One limitation of the trial is that it only included patients with pre-existing cardiovascular diseases and events. The effects of treatment on overweight or obese people without a history of cardiovascular disease were therefore not measured.
Of course, the drug’s beneficial effects on heart health were mediated by attractive weight loss. Improve your lifestyle through a balanced diet and activity physicalphysical Regular exercise is therefore important for the health of your heart.
